Liver Regenerative Effect of Phyllanthus amarus Linn. Against Alcohol Induced Liver Cell Injury in Partially Hepatectomised Albino Rats
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چکیده
منابع مشابه
Triidothyronine regulation of liver cell regeneration after alcohol-induced liver cell injury in partially hepatectomised albino rats.
Liver regeneration after partial hepatectomy (PH) has been employed as an experimental model of mammalian cell proliferation. Thymidine kinase (TK; E.C.2.7.1.21), an enzyme of the pyrimidine salvage pathway, catalyzes the phosphorylation of thymidine to thymidylate. Production of thymidylate by these enzymes is believed to be rate-limiting for DNA replication.1 The activity of this enzyme has b...
متن کاملComapartive Study on Hepatoprotective activity of Phyllanthus amarus and Eclipta prostrata against alcohol induced in albino rats
Our research studies data suggest that, there were significant variations in the observed biochemical parameters. The level of TBARS in ethanol intoxicated rats increased two fold when compared with the control animals. The levels of GSH, SOD and CAT decreased significantly in the ethanol intoxicated rats. The level of GPx was increased in the ethanol intoxicated rats. The value of vitamin E in...
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Phyllanthus niruri extract is extensively used in treating liver ailments. Effects of aqueous extract of P. niruri on liver, kidney and testes of CCl4 induced hepatotoxic rats were studied. High levels of malondialdehyde (MDA) were observed in the CCl4 test group with significant reduction of MDA levels in all groups on P. niruri extract administration. Highest levels of glutathione (GSH) were ...
متن کاملEFFECT OF ETHANOLIC EXTRACT OF PHYLLANTHUS AMARUS AND TYLOPHORA INDICA ON ISONIAZID INDUCED HEPATIC INJURY IN WISTAR ALBINO RATS. Shyamjith
Objective: To assess the hepatoprotective effect of ethanolic extract of leaves and stem of Phyllanthus amarus and ethanolic extract of leaves of Tylophora indica against Isoniazid induced liver toxicity in experimental animals. Methods: Liver toxicity was induced by administering Isoniazid 27mg/kg orally for 30 days in Wistar albino rats. Ethanolic (90%) extracts of Phyllanthus amarus (PAEE) a...
متن کاملRegenerative Effect of Bone Marrow-derived Mesenchymal Stem Cells in Thioacetamide-induced Liver Fibrosis of Rats
The present study determined the regenerative effect of bone marrow-derived stem cells (BMSCs) on thioacetamide (TA)-induced liver fibrosis in rats. A total of 30 male Wistar rats were randomly divided into sham control and treatment groups. The rats of the sham control group were subdivided into three groups and sampled on the 14th, 18th, and 20th weeks after fibrosis induction. The rats of th...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2006
ISSN: 1811-7775
DOI: 10.3923/ijp.2006.426.430